Trends in First Gabapentin and Pregabalin Prescriptions in Primary Care in the United Kingdom, 1993-2017

François Montastruc; Simone Y Loo; Christel Renoux

doi:10.1001/jama.2018.12358

Trends in First Gabapentin and Pregabalin Prescriptions in Primary Care in the United Kingdom, 1993-2017

JAMA. 2018 Nov 27;320(20):2149-2151. doi: 10.1001/jama.2018.12358.

Authors

François Montastruc¹, Simone Y Loo², Christel Renoux²

Affiliations

¹ Service de Pharmacologie Médicale et Clinique, Centre Hospitalier Universitaire, Toulouse, France.
² Centre for Clinical Epidemiology, McGill University, Montreal, Québec, Canada.

Abstract

This study examined the rates of patients in the United Kingdom treated with gabapentin and pregabalin for the first time, and the rates of these patients with an off-label indication or a coprescription of opioids or benzodiazepines.

MeSH terms

Analgesics / therapeutic use*
Analgesics, Opioid / therapeutic use
Anticonvulsants / therapeutic use
Drug Prescriptions / statistics & numerical data*
Drug Therapy, Combination / adverse effects
Drug Utilization / trends
Gabapentin / therapeutic use*
Humans
Off-Label Use / statistics & numerical data
Pregabalin / therapeutic use*
Primary Health Care
United Kingdom

Substances

Analgesics
Analgesics, Opioid
Anticonvulsants
Pregabalin
Gabapentin