Association between the reported intensity of an acute symptom at first prehospital assessment and the subsequent outcome: a study on patients with acute chest pain and presumed acute coronary syndrome

BMC Cardiovasc Disord. 2018 Nov 28;18(1):216. doi: 10.1186/s12872-018-0957-3.

Abstract

Background: To decrease the morbidity burden of cardiovascular disease and to avoid the development of potentially preventable complications, early assessment and treatment of acute coronary syndrome (ACS) are important. The aim of this study has therefore been to explore the possible association between patients' estimated intensity of chest pain when first seen by the ambulance crew in suspected ACS, and the subsequent outcome before and after arrival in hospital.

Methods: Data was collected both prospectively and retrospectively. The inclusion criteria were chest pain raising suspicion of ACS and a reported intensity of pain ≥4 on the visual analogue scale.

Results: All in all, 1603 patients were included in the study. Increased intensity of chest pain was related to: 1) more heart-related complications before hospital admission; 2) a higher proportion of heart failure, anxiety and chest pain after hospital admission; 3) a higher proportion of acute myocardial infarction and 4) a prolonged hospitalisation. However, there was no significant association with mortality neither in 30 days nor in three years. Adjustment for possible confounders including age, a history of smoking and heart failure showed similar results.

Conclusion: The estimated intensity of chest pain reported by the patients on admission by the ambulance team was associated with the risk of complications prior to hospital admission, heart failure, anxiety and chest pain after hospital admission, the final diagnosis and the number of days in hospital.

Trial registration: ClinicalTrials.gov 151:2008/4564 Identifier: NCT00792181. Registred 17 November 2008 'retrospectively registered'.

Keywords: Acute coronary syndrome; Ambulance care; Ambulance nurse; Assessment; Chest pain; Patients´ experiences.

Publication types

  • Observational Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Coronary Syndrome / complications
  • Acute Coronary Syndrome / diagnosis*
  • Acute Coronary Syndrome / mortality
  • Acute Coronary Syndrome / therapy
  • Aged
  • Aged, 80 and over
  • Ambulances
  • Angina Pectoris / diagnosis*
  • Angina Pectoris / etiology
  • Angina Pectoris / mortality
  • Angina Pectoris / therapy
  • Anxiety / diagnosis
  • Anxiety / etiology
  • Early Diagnosis
  • Emergency Medical Services*
  • Emergency Medical Technicians
  • Female
  • Health Status
  • Heart Failure / diagnosis
  • Heart Failure / etiology
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Pain Measurement*
  • Patient Admission
  • Predictive Value of Tests
  • Prognosis
  • Prospective Studies
  • Retrospective Studies
  • Severity of Illness Index
  • Time Factors

Associated data

  • ClinicalTrials.gov/NCT00792181