Elucidation of conformational diversity of druggable enzymes and classification of chemical modulators based on inhibitor-bound structures

J Biomol Struct Dyn. 2019 Oct;37(17):4563-4568. doi: 10.1080/07391102.2018.1553740. Epub 2019 Jan 9.

Abstract

Communicated by Ramaswamy H. Sarma.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Protein
  • Enzyme Inhibitors / chemistry*
  • Molecular Conformation*
  • Pharmaceutical Preparations / chemistry*
  • Protein Kinases / chemistry

Substances

  • Enzyme Inhibitors
  • Pharmaceutical Preparations
  • Protein Kinases