Characterization of the human tumor and normal tissue reactivity of the KS1/4 monoclonal antibody

Hybridoma. 1988 Aug;7(4):407-15. doi: 10.1089/hyb.1988.7.407.

Abstract

The tissue and tumor distribution of the antigen recognized by monoclonal antibody KS1/4 was determined by a combination of immunoperoxidase techniques, flow cytometric analyses and solid phase enzyme-linked immunoassays. These data document that the KS1/4 antigen is expressed in many epithelial malignancies and normal epithelial surfaces suggesting that this antigen represents an epithelial/epithelial malignancy marker.

MeSH terms

  • Antibodies, Monoclonal*
  • Antibodies, Neoplasm / immunology
  • Antigens, Neoplasm / immunology*
  • Biomarkers, Tumor / immunology*
  • Enzyme-Linked Immunosorbent Assay
  • Epithelium / immunology
  • Flow Cytometry
  • Humans
  • Immunoenzyme Techniques
  • Tissue Distribution

Substances

  • Antibodies, Monoclonal
  • Antibodies, Neoplasm
  • Antigens, Neoplasm
  • Biomarkers, Tumor