Basal Cell Carcinoma Review

Hematol Oncol Clin North Am. 2019 Feb;33(1):13-24. doi: 10.1016/j.hoc.2018.09.004.


Basal cell carcinoma (BCC) is the most common malignancy and the incidence is rising. BCCs have low mortality but can cause significant morbidity primarily through local destruction. The pathogenesis is linked to the interplay between environmental and patient-derived characteristics. There are multiple therapeutic modalities, and appropriate selection requires knowledge of complications, cosmetic outcomes, and recurrence rates. This article reviews the epidemiology, staging, treatment, and prevention of BCC.

Keywords: BCC; Basal cell carcinoma; MMS; Mohs; NMSC; Nonmelanoma skin cancer.

Publication types

  • Review

MeSH terms

  • Carcinoma, Basal Cell / diagnosis*
  • Carcinoma, Basal Cell / epidemiology
  • Carcinoma, Basal Cell / etiology
  • Carcinoma, Basal Cell / therapy*
  • Combined Modality Therapy
  • Disease Management
  • Disease Susceptibility
  • Humans
  • Incidence
  • Neoplasm Grading
  • Neoplasm Staging
  • Risk Factors
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / epidemiology
  • Skin Neoplasms / etiology
  • Skin Neoplasms / therapy
  • Treatment Outcome