Linkage of K99 production and STa activity in a plasmid of an Escherichia coli porcine isolate

Microbiol Immunol. 1988;32(6):635-9. doi: 10.1111/j.1348-0421.1988.tb01424.x.

Abstract

An Escherichia coli strain ZP118 of porcine origin was shown to harbor a 68-megadalton (Md) plasmid coding for a colonization factor K99 and heat-stable enterotoxin (STa), and a self-transmissible 51-Md plasmid coding for drug resistance. One of the transconjugants obtained by mating between ZP118 and E. coli C was found to harbor a 90-Md plasmid coding for K99, STa and drug resistance. Restriction endonuclease analysis suggested that the 90-Md plasmid could be a recombinant between the 68-Md plasmid and the 51-Md plasmid.

MeSH terms

  • Animals
  • Antigens, Surface / biosynthesis
  • Antigens, Surface / genetics*
  • Bacterial Toxins / genetics*
  • Diarrhea / microbiology
  • Diarrhea / veterinary
  • Enterotoxins / genetics*
  • Escherichia coli / genetics*
  • Escherichia coli / isolation & purification
  • Escherichia coli / metabolism
  • Escherichia coli Proteins
  • Plasmids*
  • R Factors
  • Recombination, Genetic
  • Swine
  • Swine Diseases / microbiology

Substances

  • Antigens, Surface
  • Bacterial Toxins
  • Enterotoxins
  • Escherichia coli Proteins
  • K99 antigen
  • heat stable toxin (E coli)