How eukaryotic transcriptional activators work

Nature. 1988 Oct 20;335(6192):683-9. doi: 10.1038/335683a0.


A specific protein, bound to DNA, can activate transcription of a wide array of genes in many eukaryotes. Further analysis suggests a general outline for how eukaryotic transcriptional activators function and are controlled.

Publication types

  • Review

MeSH terms

  • Animals
  • DNA-Binding Proteins / metabolism
  • Drosophila / genetics
  • Escherichia coli / genetics
  • Eukaryotic Cells
  • Gene Expression Regulation*
  • Plants / genetics
  • Transcription, Genetic*


  • DNA-Binding Proteins