Neuromuscular impairment of elbow function directly affects the activities of daily living as well as the ability to work in many patients. A series of typical pathophysiological syndromes occur in the region of the elbow as immediate or late results of local trauma or more distant injuries to the brain, cervical cord, cervicobrachial plexus, or peripheral nerves. The operative management is determined by the pathophysiology of the lesions and the anatomical relationship between the muscles and the neurovascular structures at the elbow. These syndromes and their treatment are reviewed.