Diabetes insipidus secondary to tuberculous meningoencephalitis with hypothalamic involvement extending to the hypophysis: a case report

Rev Soc Bras Med Trop. Nov-Dec 2018;51(6):865-867. doi: 10.1590/0037-8682-0455-2017.


The involvement of Mycobacterium tuberculosis in the central nervous system (CNS) is an uncommon and devastating manifestation of tuberculosis. We report a case of disseminated tuberculosis presenting as meningoencephalitis, hypothalamic involvement with extension to the hypophysis, and secondary insipidus diabetes diagnosed at autopsy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diabetes Insipidus / diagnosis
  • Diabetes Insipidus / etiology*
  • Fatal Outcome
  • Humans
  • Male
  • Meningoencephalitis / complications*
  • Meningoencephalitis / diagnosis
  • Tuberculosis, Meningeal / complications*
  • Tuberculosis, Meningeal / diagnosis