Racial and Ethnic Trends in Prostate Cancer Incidence and Mortality in Philadelphia, PA: an Observational Study

J Racial Ethn Health Disparities. 2019 Apr;6(2):371-379. doi: 10.1007/s40615-018-00534-z. Epub 2018 Dec 5.


Background: To learn more about local prostate cancer (PCa) disparities, we conducted descriptive analyses of the role of race and age in PCa using the Pennsylvania Cancer Registry data for Philadelphia (2005-2014).

Methods: We focused on the most prevalent race/ethnic groups: white (33%), black (44%), and Hispanic (9%). Outcomes included PCa rates, tumor stage, and tumor grade. Percent change was used to describe changes in age-adjusted incidence and mortality rates. Frequency tables and logistic regression models were used to describe trends in proportions of advanced PCa by race and time. Race-by-time interaction terms were retained in the models if statistically significant.

Results: PCa incidence was highest for black men over time. Incidence rates declined over time for all race groups (- 28% for white men to - 38% for Hispanic men). PCa mortality rates declined in a less universal manner (- 5% for blacks to - 32% for whites). Each year, odds increased across all race groups for advanced tumor stage (4% each year among white and Hispanic men and 9% each year among black men) and for advanced tumor grade (4% each year among white and black men and 23% each year among Hispanic men). Among younger men, black men experienced significantly increased odds of advanced tumor stage each year (8%) and Hispanics experienced significantly increased odds of advanced tumor grade each year (30%).

Conclusions: Black men remain at highest PCa risk relative to other racial/ethnic groups in Philadelphia. Younger black and Hispanic men are at particular risk for advanced PCa at diagnosis.

Keywords: Philadelphia; Prostate cancer trends; Race/ethnicity.

Publication types

  • Observational Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Black or African American
  • Hispanic or Latino
  • Humans
  • Incidence
  • Male
  • Medical Staff, Hospital
  • Middle Aged
  • Mortality / ethnology*
  • Mortality / trends
  • Neoplasm Grading
  • Neoplasm Staging
  • Odds Ratio
  • Philadelphia / epidemiology
  • Prostatic Neoplasms / ethnology*
  • Prostatic Neoplasms / mortality
  • Prostatic Neoplasms / pathology
  • White People