Sotalol

Excerpt

Sotalol is a non-cardioselective β-blocker that possesses potassium channel-blocking properties. Due to the predominant potassium channel–blocking effect, this drug is classified as a class III agent in the Vaughan-Williams classification system for antiarrhythmic medications. Sotalol is approved by the US Food and Drug Administration (FDA) and is indicated for treating hemodynamically stable ventricular tachycardia, as well as maintaining sinus rhythm, particularly in cases of paroxysmal atrial fibrillation. Intravenous loading of sotalol is recommended to facilitate the initiation of oral sotalol therapy.