Case-control study investigating parameters affecting ventilator-associated events in mechanically ventilated patients

Am J Infect Control. 2019 Apr;47(4):462-464. doi: 10.1016/j.ajic.2018.09.024. Epub 2018 Dec 4.


We analyzed a set of clinical parameters using Cox proportional hazard regressions to yield significant factors associated with the development of ventilator-associated events. In our study, intubation site, certain comorbidities, morphine, prednisone, and nutrition emerged as factors. Additionally, we presented potential mechanisms that require further research to validate.

Keywords: Critical care; Healthcare–associated infections; Risk factors; Surveillance; Time-to-event models.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Case-Control Studies
  • Clinical Decision Rules*
  • Female
  • Humans
  • Male
  • Pneumonia, Ventilator-Associated / epidemiology*
  • Respiration, Artificial / adverse effects*
  • Risk Assessment