Brain-penetrant heat shock protein amplifier arimoclomol enhances GCase activity in in vitro Gaucher disease models

EBioMedicine. 2018 Dec:38:7-8. doi: 10.1016/j.ebiom.2018.11.052. Epub 2018 Dec 3.

Authors

Aubryanna Hettinghouse¹, Chuan-Ju Liu²

Affiliations

¹ Department of Orthopaedic Surgery, New York University Medical Center, New York, NY, 10003, USA.
² Department of Orthopaedic Surgery, New York University Medical Center, New York, NY, 10003, USA; Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: chuanju.liu@nyumc.org.

No abstract available

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MeSH terms

Brain
Gaucher Disease*
Glucosylceramidase*
Heat-Shock Proteins
Humans
Hydroxylamines

Substances

Heat-Shock Proteins
Hydroxylamines
Glucosylceramidase
arimoclomol

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