In adults with osteoarthritis of the knee, is conservative management more effective than intra-articular corticosteroid injections in relieving pain?

J Okla State Med Assoc. Aug-Sep 2018;111(7):712-713.


Clinical question: In adults with osteoarthritis of the knee, do conservative management methods such as weight reduction, physical therapy, Tai Chi, non-steroidal anti-inflammatory drugs (NSAIDs), and others provide more and longer pain relief and functionality of the knee, as well as overall well-being, when compared to corticosteroid knee injections?

Answer: Yes. Although there are limited head-to-head trials directly comparing each alternative method to corticosteroid injections, overall evidence appears to indicate conservative methods as being more effective than injections, especially when considering long-term pain relief and functionality.

MeSH terms

  • Adrenal Cortex Hormones* / administration & dosage
  • Adult
  • Conservative Treatment*
  • Humans
  • Injections, Intra-Articular
  • Osteoarthritis, Knee* / complications
  • Osteoarthritis, Knee* / therapy
  • Pain
  • Pain Management*


  • Adrenal Cortex Hormones