Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Nov;72(5):325-329.
doi: 10.5455/medarh.2018.72.330-334.

The Importance of Acinetobacter Species in the Hospital Environment

Affiliations
Free PMC article

The Importance of Acinetobacter Species in the Hospital Environment

Velma Rebic et al. Med Arch. .
Free PMC article

Abstract

Introduction: Acinetobacter species is associated with health care associated infections especially in patients on respiratory therapy equipment and indwelling catheters. They are becoming increasingly drug resistant. The knowledge of the prevalence and pattern of antimicrobial susceptibility pattern of Acinetobacter spp. is important.

Aims: The study is undertaken to estimate the prevalence rate, risk factors and antimicrobial resistance pattern of isolates. in Acinetobacter spp. from various clinical samples.

Material and methods: The isolates of Acinetobacter species obtained from various clinical specimen. Specimens were processed by standard microbiological techniques. Antimicrobial sensitivity tests of the Acinetobacter isolates were done by modified Kirby-Bauer disc diffusion method.

Results: Out of 622 isolates, 399 isolates were from inpatients (62,18%) and 223 were from outpatients (37,82%). More than 90% of isolates displayed resistance to ampicillin, amoxicillin-clavulanic acid, ceftazidime, caftriaxon and amikacin. Resistance to gentamicin, co-trimoxazole and ciprofloxacin were also common. Least resistance was seen to piperacillin-tazobactam and imipenem. A total of 125 Acinetobacter isolates were analyzed, out of which 78.4 % were multi-drug resistant (MDR). Of these MDR isolates, 17.24% were pan-resistant. A. baumannii was the most common species responsible for wound infection (84,8%), pneumonia(96,15%), abscess (72.7%), urinary tract infection (85,7%) and septicemia(89,5%).

Conclusion: Multi-drug resistant Acinetobacter has emerged as an important nosocomial pathogen. Antibiotic susceptibility testing is critical in the treatment of infections caused by Acinetobacter. Continued surveillance of prevalent organisms in ICUs, combined with preventive measures remains absolutely essential in efforts to prevent or limit the spread of Acinetobacter infection.

Keywords: Acinetobacter; antimicrobial resistance; hospital.

Figures

Figure 1.
Figure 1.. Age-wise distribution of Acinetobacter isolates
Figure 2.
Figure 2.. Distribution of Acinetobacter isolates in hospital wards.
Figure 3.
Figure 3.. Sample-wise distribution of Acinetobacter isolates

Similar articles

See all similar articles

Cited by 1 article

References

    1. Tabassum S. Multidrug-resistant (MDR) Acinetobacter: a major Nosocomial pathogen challenging physicians. Bangladesh J Med Microbiol. 2007;01(02):65–68.
    1. Peleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: Emergence of a successful pathogen. Clin Microbiol Rev. 2008;21(3):538–582. - PMC - PubMed
    1. Sunenshine RH, Wright MO, Maragakis LL, Harris AD, Song X, Hebden J, et al. Multidrug-resistant acinetobacter infection mortality rate and length of hospitalization. Emerg Infect Dis. 2007;13:97–103. - PMC - PubMed
    1. Collee JG, Fraser AG, Marmion BP, Simmons A. 14th ed. New York: Churchill-Livingstone; Mackie and McCartney Practical Medical Microbiology.
    1. Koneman EW, Allen SD, Jande WM, Schreckenberger PC, Winn WC., Jr . 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2006. Koneman’s Colour Atlas and Textbook of Diagnostic Microbiology.

Substances

Feedback