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. 2019 Apr;19(2):164-167.
doi: 10.1136/practneurol-2018-002105. Epub 2018 Dec 8.

Diabetic Amyotrophy: A Painful Radiculoplexus Neuropathy


Diabetic Amyotrophy: A Painful Radiculoplexus Neuropathy

Dafydd Llewelyn et al. Pract Neurol. .


Diabetic lumbosacral radiculoplexus neuropathy is a monophasic syndrome of diffuse pain and weakness that typically affects the lower limbs asymmetrically and is often associated with significant weight loss. Recovery can be prolonged and unpredictable. It is a clinical diagnosis and investigations are performed mainly to exclude other causes. Although it is most likely caused by a microvasculitis, there is no evidence to support using intravenous immunoglobulin or any long-term immunosuppression. Pulsed methylprednisolone may help pain if given within 2-3 months of symptom onset.

Conflict of interest statement

Competing interests: None declared.

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