1 From the Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio (D.I.S.) Peter MacCallum Cancer Centre, Melbourne, Australia Sir Peter MacCallum Department of Oncology and Centre for Integrated Critical Care, University of Melbourne, Parkville, Australia Cancer and Neural-Immune Research Laboratory, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia (B.R.).