Complete Genome Sequences of Canadian Epidemic Methicillin-Resistant Staphylococcus aureus Strains CMRSA3 and CMRSA6

Jo-Ann McClure; Steven M Shideler; Kunyan Zhang

doi:10.1128/MRA.00892-18

Complete Genome Sequences of Canadian Epidemic Methicillin-Resistant Staphylococcus aureus Strains CMRSA3 and CMRSA6

Microbiol Resour Announc. 2018 Aug 9;7(5):e00892-18. doi: 10.1128/MRA.00892-18. eCollection 2018 Aug.

Authors

Jo-Ann McClure¹, Steven M Shideler², Kunyan Zhang^{1

3

2

4

5}

Affiliations

¹ Centre for Antimicrobial Resistance, Alberta Health Services/Calgary Laboratory Services/University of Calgary, Calgary, Alberta, Canada.
² Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada.
³ Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada.
⁴ Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
⁵ The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 8 (CC8) sequence type 239 (ST239) represents a predominant hospital-associated MRSA sublineage present worldwide. The Canadian epidemic MRSA strains CMRSA3 and CMRSA6 are moderately virulent members of this group but are closely related to the highly virulent strain TW20. Whole-genome sequencing of CMRSA3 and CMRSA6 was conducted to identify genetic determinants associated with their virulence.