Purpose: The study compared the mechanical behavior of bioresorbable polymeric stents with various designs during deployment, and investigated their fatigue performance under pulsatile blood pressure loading.
Methods: Finite element simulations have been carried out to compare the mechanical performance of four bioresorbable polymeric stents, i.e., Absorb, Elixir, Igaki-Tamai and RevaMedical, during deployment in diseased artery. Tri-folded balloon was modelled to expand the crimped stent onto the three-layered arterial wall with plaque. Cyclic diastolic-systolic pressure loading was applied to both stent and arterial wall to study fatigue behavior.
Results: Stents with larger U-bend and longer axial strut demonstrate more flexibility but suffer from severe dogboning and recoiling effects. Stress concentrations in the stent, as well as in the plaque and artery, are higher for stents designed with increased rigidity such as those with smaller U-bends and shorter axial struts. Simulations of fatigue deformation for Elixir stent demonstrate that the U-bends, with high stress concentrations, have a potential risk of fatigue failure under pulsatile systolic-diastolic blood pressure as opposed to the counter metallic stents which are normally free of fatigue failure.
Conclusion: The structural behaviour of bioresorbable polymeric stent is strongly affected by its design, in terms of expansion, dogboning, recoiling and stress distribution during the deployment process.
Keywords: Bioresorbable polymeric stents; Fatigue life; Finite element; Recoiling and dogboning; Stent expansion.