Autoimmune and angiogenic biomarkers in autoimmune atherosclerosis

Clin Immunol. 2019 Feb;199:47-51. doi: 10.1016/j.clim.2018.12.011. Epub 2018 Dec 10.


Several inflammatory, proteolytic, angiogenic and bone-associated factors play a role in the development of autoimmune, accelerated atherosclerosis in rheumatic diseases. Some of these may serve as biomarkers of vascular pathology and may be useful in the follow-up of vascular damage and outcome. Multi-biomarker profiles rather than a single markers would likely be optimal in this respect.

Keywords: Angiogenesis; Autoimmune atherosclerosis; Autoimmunity; Biomarkers; Cardiovascular disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Atherosclerosis / etiology
  • Atherosclerosis / genetics
  • Atherosclerosis / immunology*
  • Atherosclerosis / therapy
  • Autoantibodies / blood
  • Autoimmune Diseases / etiology
  • Autoimmune Diseases / genetics
  • Autoimmune Diseases / immunology*
  • Autoimmune Diseases / therapy
  • Biomarkers
  • Environment
  • Humans
  • Neovascularization, Pathologic*


  • Autoantibodies
  • Biomarkers