Tumour devascularisation as a potential immunotherapeutic strategy

Oncoimmunology. 2018 Oct 11;8(1):e1526614. doi: 10.1080/2162402X.2018.1526614. eCollection 2019.

Abstract

Complete tumour devascularisation (CTD) is a surgical technique which entails the complete disruption by ligation or cutting of afferent and efferent tumour vasculature which remains in situ. In some animal models, CTD induces immune responses that lead to regression of distant metastases and protective immunity.

Keywords: Immunotherapy; cancer; devascularisation; ischaemia; tumour ligation.

Publication types

  • Research Support, Non-U.S. Gov't

Grants and funding

Publication fee has been covered by an unrestricted grant from Roche to the First Faculty of Medicine, Charles University, Prague, Czech Republic.