Incidence of osteonecrosis and insufficiency fracture of the hip and knee joints based on MRI in 300 renal transplant patients

Hip Int. 2019 May;29(3):316-321. doi: 10.1177/1120700018808693. Epub 2018 Nov 1.

Abstract

Introduction: The purpose of this study was to investigate the incidence of necrosis and insufficiency fracture of the hip and knee using magnetic resonance imaging (MRI) in renal transplant patients.

Methods: We examined 300 consecutive renal transplant patients using MRI of the hips and knees (T1-weighted coronal MRI) preoperatively and at 3 and 6 months postoperatively. Oblique axial-plane T1-weighted MRI and short-tau inversion-recovery T2-weighted MRI were performed parallel to the femoral neck when distinguishing the osteonecrosis of the femoral head (ONFH) from subchondral insufficiency fracture (SIF) of the femoral head was difficult.

Results: ONFH was observed in 3 hips (3 cases, 1.0%). Osteonecrosis of the knee was observed in 2 knees (1 case, 0.3%). SIF of the femoral head was observed in 5 hips (3 cases, 1.0%). Bilateral simultaneous onset of SIF of the femoral head was observed in 2 cases (0.7%). Insufficiency fracture of the knee was observed in 2 knees (1 case, 0.3%).

Conclusions: When it was difficult to distinguish ONFH from SIF of the femoral head, oblique axial-plane T1-weighted MRI and the short-tau inversion-recovery T2-weighted MRI parallel to the femoral neck were useful to establish the correct diagnosis.

Keywords: Femoral head; osteonecrosis; renal transplantation; subchondral insufficiency fracture.

MeSH terms

  • Adult
  • Aged
  • Female
  • Femur Head / pathology*
  • Femur Head Necrosis / diagnosis
  • Femur Head Necrosis / epidemiology*
  • Femur Head Necrosis / etiology
  • Fractures, Stress / epidemiology*
  • Fractures, Stress / etiology
  • Hip Fractures / diagnosis
  • Hip Fractures / epidemiology*
  • Hip Fractures / etiology
  • Humans
  • Incidence
  • Japan / epidemiology
  • Kidney Transplantation / adverse effects*
  • Knee Joint / diagnostic imaging*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Young Adult