Skin aging is a complex biological process that arises from two basic processes: intrinsic aging (influenced by genetics factors, cellular metabolism, hormone, and metabolic processes) and extrinsic aging caused by chronic light exposure, pollution, ionizing radiation, chemicals, toxins (Expert Opin Biol Ther. 2008;8:393). Intrinsic aging called also chronological aging is observed in sun-protected skin of elderly persons. Microneedling, as the term indicates, means the use of needles or "microneedles" to achieve a therapeutic effect. The technique of microneedling was innovated by Fernandes. Safe treatment for facial wrinkles due to both (aging and smoking) and Dermapen is an effective and all skin types with the advantage of being an inexpensive office maneuver and relatively risk-free procedure, avoiding significant downtime depigmentation or complication.
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