RETRACTED: Knockdown of lncRNA-H19 inhibits cell viability, migration and invasion while promotes apoptosis via microRNA-143/RUNX2 axis in retinoblastoma

Biomed Pharmacother. 2019 Jan:109:798-805. doi: 10.1016/j.biopha.2018.10.096. Epub 2018 Nov 5.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Given the comments of Dr Elisabeth Bik regarding this article “In almost all papers, Western blot panels within the same figure, and across figures and papers, appear to share the same background, while the bands are regularly spaced, all have similar rounded edges without the usual smudges and specks, and with some bands showing a recognizable “jumping sardine” shape”, the journal requested the authors to provide the raw data. However, the authors were not able to fulfil this request and therefore the Editor-in-Chief decided to retract the article.

Keywords: PI3K/AKT/mTOR; RUNX2; Retinoblastoma; lncRNA-H19; microRNA-143.

Publication types

  • Retracted Publication

MeSH terms

  • Apoptosis / physiology
  • Cell Movement / physiology*
  • Cell Survival / physiology
  • Core Binding Factor Alpha 1 Subunit / metabolism*
  • Gene Knockdown Techniques / methods
  • Humans
  • MicroRNAs / metabolism*
  • Neoplasm Invasiveness / pathology
  • Neoplasm Invasiveness / prevention & control
  • RNA, Long Noncoding / antagonists & inhibitors
  • RNA, Long Noncoding / biosynthesis*
  • Retinal Neoplasms / metabolism*
  • Retinal Neoplasms / pathology
  • Retinoblastoma / metabolism*
  • Retinoblastoma / pathology

Substances

  • Core Binding Factor Alpha 1 Subunit
  • H19 long non-coding RNA
  • MIRN143 microRNA, human
  • MicroRNAs
  • RNA, Long Noncoding
  • RUNX2 protein, human