Omics approaches to study juvenile hormone synthesis

Abstract

The juvenile hormones (JHs) are a family of insect acyclic sesquiterpenoids produced by the corpora allata (CA), a pair of endocrine glands connected to the brain. They are involved in the regulation of development, reproduction, behavior, caste determination, diapause, stress response, and numerous polyphenisms. In the post-genomics era, comprehensive analyses using functional 'omics' technologies such as transcriptomics, proteomics and metabolomics have increased our understanding of the activity of the minute CA. This review attempts to summarize some of the 'omics' studies that have contributed to further understand JH synthesis in insects, with an emphasis on our own research on the mosquito Aedes aegypti.