Interleukin-1α as an intracellular alarmin in cancer biology

Semin Immunol. 2018 Aug:38:3-14. doi: 10.1016/j.smim.2018.10.006. Epub 2018 Oct 26.
No abstract available

Keywords: Anti-tumor immunity and immunotherapy; IL-1; Inflammation; Tumor invasiveness and metastases.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alarmins / antagonists & inhibitors
  • Alarmins / immunology*
  • Alarmins / metabolism
  • Animals
  • Antibodies, Neutralizing / immunology
  • Antibodies, Neutralizing / therapeutic use
  • Humans
  • Interleukin-1alpha / antagonists & inhibitors
  • Interleukin-1alpha / immunology*
  • Interleukin-1alpha / metabolism
  • Intracellular Space / drug effects
  • Intracellular Space / immunology*
  • Intracellular Space / metabolism
  • Neoplasms / drug therapy
  • Neoplasms / immunology*
  • Neoplasms / metabolism
  • Treatment Outcome
  • Tumor Microenvironment / drug effects
  • Tumor Microenvironment / immunology

Substances

  • Alarmins
  • Antibodies, Neutralizing
  • Interleukin-1alpha