YMCA exercise intervention to augment smoking cessation treatment in adults with high anxiety sensitivity: Study protocol for a randomized controlled trial

Contemp Clin Trials. 2019 Feb;77:1-7. doi: 10.1016/j.cct.2018.12.001. Epub 2018 Dec 15.


Extant evidence suggests that exercise can reduce anxiety related vulnerability factors, such as anxiety sensitivity (AS), or fear of bodily sensations related to anxiety, that negatively impact smoking cessation outcomes. Building upon emerging evidence supporting the efficacy of exercise as an aid for smoking cessation in adults with high AS, we are conducting a trial to examine the efficacy and feasibility of this clinical application when implemented in a community setting. Partnering with the YMCA, this study aims to enroll 150 adults in a standard smoking cessation protocol (i.e. counseling and nicotine replacement therapy) and randomly assign them to either 15 weeks of programmed vigorous-intensity or low-intensity exercise. Smoking abstinence data will be collected up to 6 months following the quit attempt.

Publication types

  • Clinical Trial Protocol
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Anxiety / therapy*
  • Counseling / methods
  • Exercise Therapy / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Research Design
  • Sex Factors
  • Smoking Cessation / methods*
  • Smoking Cessation / psychology*
  • Socioeconomic Factors
  • Tobacco Use Cessation Devices
  • Young Adult