Digestive disorders and Intestinal microbiota

Acta Biomed. 2018 Dec 17;89(9-S):47-51. doi: 10.23750/abm.v89i9-S.7912.

Abstract

In the last decade, a barge body of scientific literature has suggested that specific alterations of the gut microbiota may be associated with ther development and clinical course of several gastrointestinal diseases, including irritable bowel syndrome, inflammatory bowel disease, celiac disease, gastrointestinal cancer and Clostridium difficile infection. These alterations are often referred to as "dysbiosis", a generic term designing reduction of gut microbiota biodiversity and alterations in its composition. Here, we provide a synthetic overview of the key concepts on the relationship between intestinal microbiota and gastrointestinal diseases, focusing on the translation of these concepts into clinical practice.

Publication types

  • Review

MeSH terms

  • Biodiversity
  • Celiac Disease / microbiology
  • Clostridioides difficile
  • Clostridium Infections / microbiology
  • Digestive System Diseases / etiology
  • Digestive System Diseases / microbiology*
  • Digestive System Neoplasms / etiology
  • Digestive System Neoplasms / microbiology
  • Disease Susceptibility
  • Dysbiosis / complications*
  • Dysbiosis / therapy
  • Endotoxins / metabolism
  • Gastrointestinal Microbiome*
  • Humans
  • Inflammatory Bowel Diseases / microbiology
  • Intestinal Absorption
  • Irritable Bowel Syndrome / microbiology
  • Irritable Bowel Syndrome / physiopathology
  • Liver Diseases / microbiology

Substances

  • Endotoxins