In a large community-randomized trial, biannual azithromycin distributions significantly reduced postneonatal childhood mortality in sub-Saharan African sites. Here, we present a prespecified secondary analysis showing that much of the protective effect was in the first 3 months postdistribution. Distributing more frequently than biannually could be considered if logistically feasible. Clinical Trials Registration. NCT02047981.
Keywords: azithromycin; childhood mortality; sub-Saharan Africa.
© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America.