Oriented Cell Division: The Pull of the Pole

Dev Cell. 2018 Dec 17;47(6):686-687. doi: 10.1016/j.devcel.2018.11.040.


Cells are thought to divide along their longest axis. Now, two studies in Developmental Cell (Scarpa et al., 2018) and EMBO Journal (Finegan et al., 2018) reveal that in many instances, cell division orientation in vivo is not determined by cell shape, but rather by local anisotropies in cell mechanics.

Publication types

  • Comment

MeSH terms

  • Actomyosin*
  • Cell Division
  • Cell Shape
  • Epithelial Cells
  • Spindle Apparatus*


  • Actomyosin