Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 25 (4), 227-233

Effect of Sarcopenia on Postoperative Mortality in Osteoporotic Hip Fracture Patients


Effect of Sarcopenia on Postoperative Mortality in Osteoporotic Hip Fracture Patients

You Keun Kim et al. J Bone Metab.


Background: Few studies have investigated the effects of sarcopenia on postoperative outcomes including mortality rates following surgery for osteoporotic hip fractures. The purpose of the present study was to determine the prevalence of sarcopenia and the relationship between sarcopenia and 1- and 5-year mortality rates in a consecutive series of patients with osteoporotic hip fractures.

Methods: Among patients who underwent hip surgery for osteoporotic hip fractures, this study included 91 patients subjected to abdominal computed tomography within 1 year of hip surgery. We defined sarcopenia using sex-specific cut-off points for the skeletal muscle index at the level of the third lumbar vertebra. All patients were divided into 2 groups according to the presence or absence of sarcopenia and the 1- and 5-year mortality rates were compared. To confirm factors affecting mortality in addition to sarcopenia, we examined patient age, sex, American Society of Anesthesiologists grade, location of fracture, type of surgery, and bone mineral density.

Results: The 1- and 5-year mortality rates were 20.9% and 67.2%, respectively. Among the 45 patients with sarcopenia, the 1- and 5-year mortality rates were 22.2% and 82.7%, respectively. Of the 46 patients without sarcopenia, the 1- and 5-year mortality rates were 19.6% and 52.7%, respectively. Results of the Kaplan-Meier analysis showed that sarcopenia did not affect the 1-year mortality rate (P=0.793), but had a significant effect on the 5-year mortality rate (P=0.028). Both perioperative sarcopenia (P=0.018) and osteoporosis (P=0.000) affected the 5-year mortality rate.

Conclusions: Sarcopenia increases the risk of 5-year mortality in patients with osteoporotic hip fractures.

Keywords: Hip fractures; Mortality; Osteoporotic fractures; Sarcopenia.

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.


Fig. 1
Fig. 1. Flow chart presenting the study subjects. CT, computed tomography; DXA, dual energy X-ray absorptiometry.
Fig. 2
Fig. 2. Kaplan-Meier survival curve. Bold line is for non-sarcopenic patients. Fine line is for sarcopenic patients.

Similar articles

See all similar articles


    1. Folbert EC, Hegeman JH, Vermeer M, et al. Improved 1-year mortality in elderly patients with a hip fracture following integrated orthogeriatric treatment. Osteoporos Int. 2017;28:269–277. - PubMed
    1. Osnes EK, Lofthus CM, Meyer HE, et al. Consequences of hip fracture on activities of daily life and residential needs. Osteoporos Int. 2004;15:567–574. - PubMed
    1. Choi HJ, Shin CS, Ha YC, et al. Burden of osteoporosis in adults in Korea: a national health insurance database study. J Bone Miner Metab. 2012;30:54–58. - PubMed
    1. Canale ST, Beaty JH. Campbell's operative orthopaedics. 11th ed. Philadelpia, PA: Mosby Elsevier Corp.; 2008.
    1. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–423. - PMC - PubMed