Ascorbic acid (AA), uric acid (UA), and dopamine (DA) are biologically important molecules which have similar structures and important tasks in the human body. Since they usually coexist in biological fluids and oxidize at overlapping potentials; developing a sensitive, selective, simple, fast, and affordable electroanalytical method for simultaneous determination of AA, UA, and DA has always been a prominent research subject. Voltammetry has become one of the most commonly used and important method amongst the other methods due to its high sensitivity and reliability. Moreover, nanomaterials have become very popular in electrochemistry recently with the use of nanosensors in determinations of molecules thanks to unique properties of nanomaterials. This review highlights the most widely used voltammetric methods and nanomaterials in simultaneous electrochemical sensing of AA, UA, and DA; provides an overview of recent studies on simultaneous determination of AA, UA, and DA, and also explains the interference effect of AA, UA, and DA to each other.
Keywords: Ascorbic acid; dopamine; nanosensor; uric acid; voltammetry.