Treatment of Ruptured Intracranial Aneurysms Using the Woven EndoBridge Device: A Two-Center Experience

World Neurosurg. 2019 Mar:123:e709-e716. doi: 10.1016/j.wneu.2018.12.010. Epub 2018 Dec 19.


Background: The Woven EndoBridge (WEB) device is a new treatment modality developed for broad-necked unruptured intracranial aneurysms (IAs) but shows potential for the treatment of ruptured IAs as well. Our aim was to describe 6-month aneurysm obliteration rates, clinical outcomes, and procedure-related complications after WEB treatment for ruptured IAs from 2 academic centers.

Methods: We conducted a retrospective observational study, including all consecutive patients treated with the WEB device (WEB single layer and single-layer sphere) for a ruptured IA causing acute subarachnoid hemorrhage between 2014 (start of use) and 2017. Primary outcome was angiographic aneurysm obliteration (Beaujon Occlusion Scale Score) rate. Secondary outcomes were early re-bleedings, complications, and patient outcome (death and modified Rankin Scale).

Results: A total of 33 patients with ruptured IAs were treated 0-4 days from IA rupture. Of 27 survivors, 6-month angiographic follow-up was available for 26 patients, of whom 81% showed complete occlusion. Of the 27 survivors, 24 patients (89%) had a favorable neurologic outcome at 6 months after subarachnoid hemorrhage. Two aneurysms were retreated (8% of all). There was 1 fatal procedure-related complication. No early aneurysm re-bleedings were noted.

Conclusions: For anatomically suitable ruptured IAs, WEB device treatment seems to be safe and results in acceptable occlusion rates. Still, larger studies with long-term results are needed before recommendations can be made.

Keywords: Intracranial aneurysm; Stroke; Subarachnoid hemorrhage; WEB; Woven EndoBridge device.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Aneurysm, Ruptured / therapy*
  • Embolization, Therapeutic / instrumentation*
  • Endovascular Procedures / instrumentation
  • Equipment Design
  • Humans
  • Intracranial Aneurysm / therapy*
  • Length of Stay
  • Middle Aged
  • Postoperative Complications / etiology
  • Recurrence
  • Retrospective Studies
  • Subarachnoid Hemorrhage / therapy
  • Thromboembolism / etiology
  • Treatment Outcome