Initial Experience With Hand-Assisted Laparoscopic Living Donor Nephrectomy: Training and Clinical Practice as a General Surgeon

Transplant Proc. 2018 Dec;50(10):3113-3120. doi: 10.1016/j.transproceed.2018.08.052. Epub 2018 Sep 6.

Abstract

Background: To analyze our initial results of hand-assisted laparoscopic living donor nephrectomy, executed by a skilled gastrointestinal surgeon.

Methods: A total of 22 consecutive patients underwent the hand-assisted laparoscopic living donor nephrectomy between December 2014 and January 2017. We retrospectively analyze the patient's perioperative clinical data, which were collected prospectively.

Results: The right kidney was harvested in 12 patients. The mean operative time and intraoperative blood loss was 241.0 ± 43.4 minutes (range, 140-310 min) and 293.2 ± 203.1 mL (range, 50-700 mL), respectively. The mean warm ischemic time was 288.4 ± 103.4 seconds (range, 179-610 s). Postoperative complications included chyle leakage in 2 patients who were left kidney donors and oliguria in 1 patient who was a right kidney donor. All patients recovered with conservative care, and the mean hospital stay was 7.5 ± 1.7 days. The mean creatinine level was 0.7 ± 0.2 mg/dL before surgery, 1.1 ± 0.3 mg/dL at postoperative day (POD) 1, and 1.0 ± 0.2 mg/dL after discharge. The mean glomerular filtration rate was 97.9 ± 18.2 mL/min/1.73 m2 before surgery, 60.7 ± 10.4 at POD 1, and 67.3 ± 11.1 after discharge. Operation time was not associated with patient body mass index and case number. No significant differences, other than postoperative complications, were found in the perioperative data for the side of kidney donation.

Conclusion: A skilled surgeon with experience in laparoscopic abdominal surgery (such as gastrectomy or colectomy) might safely perform hand-assisted donor nephrectomy. However, we could not identify a clear case number to complete the learning curve.

MeSH terms

  • Adult
  • Blood Loss, Surgical
  • Female
  • General Surgery / education*
  • Glomerular Filtration Rate
  • Hand-Assisted Laparoscopy / adverse effects
  • Hand-Assisted Laparoscopy / education*
  • Hand-Assisted Laparoscopy / methods
  • Humans
  • Kidney Transplantation / adverse effects
  • Kidney Transplantation / education*
  • Kidney Transplantation / methods
  • Learning Curve
  • Length of Stay
  • Living Donors
  • Male
  • Middle Aged
  • Nephrectomy / adverse effects
  • Nephrectomy / education*
  • Nephrectomy / methods
  • Operative Time
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Tissue and Organ Harvesting / education*
  • Tissue and Organ Harvesting / methods
  • Warm Ischemia