Background: The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) research program aims to defeat the rising HIV epidemic among adolescents and young adults in the United States.
Objective: This study aims to optimize cross-study analyses and comparisons of standardized measures (variables) collected in the ATN.
Methods: Guidelines were developed for harmonizing measures to be collected across ATN studies.
Results: Eight domains were identified for harmonization-Demographics and Socioeconomic Characteristics, Sexual Behavior and Risk, Substance Use and Abuse, HIV-Positive Cascade, HIV-Negative Cascade, Mental Health, Social Support and Isolation, and Pre-exposure Prophylaxis Cascade.
Conclusions: The collection of selected key measures in a uniform manner across studies facilitates the characterization of participant populations, comparisons between studies, and pooled analysis of data from multiple studies.
Keywords: Adolescent Medicine Trials Network for HIV/AIDS Interventions; HIV; adolescent; data harmonization.
©Micah McCumber, Demetria Cain, Sara LeGrand, Kenneth H Mayer, Debra A Murphy, Matthew A Psioda, Arlene C Seña, Tyrel J Starks, Michael Hudgens. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 21.12.2018.