Colitis in calves: natural and experimental infection with a verotoxin-producing strain of Escherichia coli O111:NM

Can J Vet Res. 1988 Oct;52(4):484-7.

Abstract

Verotoxin-producing Escherichia coli O111:NM were isolated from two five week old Holstein calves with dysentery. On necropsy both calves had pseudomembranous ileitis, mucohemorrhagic colitis and proctitis. Large numbers of E. coli O111:NM were isolated from the colon and lesions typical of attaching-and-effacing E. coli were evident. The isolates from both calves had identical biochemical reactions and antimicrobial resistance patterns. Oral inoculation of a four day old colostrum deprived calf with 1 x 10(10) organisms of E. coli O111:NM produced a mild, focal colitis with typical attachment and effacement lesions. We conclude that the strain of E. coli O111:NM isolated from the clinical cases has the ability to produce colitis characterized by attachment and effacement of the colonic mucosa.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Bacterial Toxins*
  • Cattle
  • Cattle Diseases / microbiology*
  • Cattle Diseases / pathology
  • Colitis / microbiology
  • Colitis / pathology
  • Colitis / veterinary*
  • Escherichia coli / classification*
  • Escherichia coli Infections / pathology
  • Escherichia coli Infections / veterinary*
  • Male
  • Shiga Toxin 1

Substances

  • Bacterial Toxins
  • Shiga Toxin 1