Vitamin B1 for type B metabolic acidosis: An underrecognized approach

Saudi J Kidney Dis Transpl. 2018 Nov-Dec;29(6):1480-1483. doi: 10.4103/1319-2442.248314.

Abstract

Lactic acidosis is a life-threatening and rather common complication and reason for consultation to the nephrologist. The cause for this condition is usually thought to be secondary to hypoperfusion and ischemia collectively. However, many other rare causes have been described, yet there is little awareness of these, consequently delaying optimal care. We present a multifactorial case of lactic acidosis due to thiamine deficiency, liver disease, and lymphoma; all underrecognized causes of Type B lactic acidosis.

Publication types

  • Case Reports

MeSH terms

  • Acid-Base Equilibrium / drug effects*
  • Acidosis, Lactic / diagnosis
  • Acidosis, Lactic / drug therapy*
  • Acidosis, Lactic / etiology
  • Acidosis, Lactic / physiopathology
  • Aged
  • Fatal Outcome
  • Humans
  • Liver Neoplasms / complications*
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / therapy
  • Lymphoma, Mantle-Cell / complications*
  • Lymphoma, Mantle-Cell / diagnosis
  • Lymphoma, Mantle-Cell / therapy
  • Male
  • Thiamine / therapeutic use*
  • Thiamine Deficiency / complications
  • Thiamine Deficiency / diagnosis
  • Thiamine Deficiency / drug therapy*
  • Treatment Outcome
  • Urinary Bladder Neoplasms / complications*
  • Urinary Bladder Neoplasms / diagnosis
  • Urinary Bladder Neoplasms / therapy
  • Vitamin B Complex / therapeutic use*

Substances

  • Vitamin B Complex
  • Thiamine