Volumetric stereotactic surgical resection of intra-axial brain mass lesions

Mayo Clin Proc. 1988 Dec;63(12):1186-98. doi: 10.1016/s0025-6196(12)65405-6.


From August 1984 to August 1987 at the Mayo Clinic, 226 computer-assisted stereotactic resections based on computed tomography or magnetic resonance imaging (or both) were performed on 203 supratentorial and 23 infratentorial lesions in various deep-seated or essential brain locations. Histologic examination revealed 112 glial neoplasms, 70 nonglial tumors, and 44 nonneoplastic lesions. The overall morbidity was 9.3% (21 of 226 patients were worse after the procedure), and the 30-day operative mortality was 1% (2 patients). The procedure provides maximal cytoreduction in high-grade glial neoplasms but is most beneficial to patients who have histologically circumscribed tumors, such as pilocytic astrocytomas, metastatic neoplasms, and miscellaneous nonglial and nonneoplastic lesions.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brain Neoplasms / surgery*
  • Cerebrovascular Disorders / surgery
  • Child
  • Child, Preschool
  • Humans
  • Intracranial Arteriovenous Malformations / surgery
  • Magnetic Resonance Imaging
  • Middle Aged
  • Postoperative Complications / etiology
  • Stereotaxic Techniques* / instrumentation
  • Stereotaxic Techniques* / mortality
  • Therapy, Computer-Assisted*
  • Tomography, X-Ray Computed