Cancer Patients' Symptom Burden and Health-related Quality of Life (HRQoL) at Tertiary Cancer Center from 2006 to 2013: A Cross-sectional Study

Anticancer Res. 2019 Jan;39(1):271-277. doi: 10.21873/anticanres.13107.

Abstract

Background/aim: To observe changes in symptoms and health-related quality of life (HRQoL) over 7 years among cancer patients at different stages of the disease.

Patients and methods: This prospective cross-sectional study at the Helsinki University Hospital Cancer Center, was carried out in 2006 and repeated in 2013. All participants filled in the EORTC-QLQ-C30 questionnaire.

Results: Altogether, 581 patients responded (49% in 2006 and 54% in 2013). The disease was local in 51% and advanced in 49% of patients. The HRQoL was significantly lower, except for emotional and cognitive functions, and the symptom burden more severe in advanced cancer. The most prevalent symptoms were fatigue (93% and 85%; moderate/severe 22% and 9%), pain (65% and 47%; moderate/severe 16% and 5%), and insomnia (64% and 60%; moderate/severe 20 and 21%), respectively. No changes in HRQoL or symptoms were found at 7 years.

Conclusion: There is a need for early integrated palliative care to improve HRQoL during cancer treatments.

Keywords: Health-related quality of life; neoplasms; palliative care; symptoms.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasms / epidemiology*
  • Neoplasms / pathology
  • Pain / epidemiology*
  • Pain / pathology
  • Palliative Care*
  • Quality of Life
  • Surveys and Questionnaires
  • Tertiary Care Centers