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Review
. 2018 Dec 29;44(1):152.
doi: 10.1186/s13052-018-0595-5.

Listeria Monocytogenes Meningitis in Immunocompetent and Healthy Children: A Case Report and a Review of the Literature

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Free PMC article
Review

Listeria Monocytogenes Meningitis in Immunocompetent and Healthy Children: A Case Report and a Review of the Literature

Massimo Luca Castellazzi et al. Ital J Pediatr. .
Free PMC article

Abstract

Background: Listeria monocytogenes is a gram-positive bacteria generally transmitted to humans through ingestion of contaminated food. It typically infects high risk subjects, such as pregnant women, neonates, the elderly and immunocompromised patients. Listeria meningitis is rarely reported in previously healthy children with no immunological disorders. However, it can be aggressive in such subjects and is associated with a high mortality rate. Prompt diagnosis is essential so that adequate antibiotic treatment can be started and the best outcome achieved.

Case presentation: We report the case of a previously healthy 16-month-old child with Listeria meningitis who was successfully treated with intravenous ampicillin and gentamicin without any sequelae.

Conclusions: Although Listeria meningitis is rare in previously healthy immunocompetent children, it must be considered, especially in children who do not improve with first-line antibiotic treatment. A review of the literature published since 1996 has been performed, to provide a general overview on this topic.

Keywords: Immunocompetent child; Listeria monocytogenes; Meningitis.

Conflict of interest statement

Ethics approval and consent to participate

This case report was approved by the Ethics Committee of Fondazione IRCCS Ca′ Granda Ospedale Maggiore Policlinico, Milan, Italy. For case reports, the Ethics Committee of Fondazione IRCCS Ca′ Granda Ospedale Maggiore Policlinico does not provide a reference number.

Consent for publication

Written informed consent for the publication of this case report was obtained from the patient’s parents. A copy of the written consent is available for review by the Editor-in-Chief of this journal.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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