Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus

Epilepsy Behav Case Rep. 2018 Jul 17:10:141-144. doi: 10.1016/j.ebcr.2018.07.004. eCollection 2018.


We present the case of a child with long-standing, super-refractory status epilepticus (SRSE) who manifested prompt and complete resolution of SRSE upon exposure to pure cannabidiol. SRSE emerged in the context of remote suspected encephalitis with previously well-controlled epilepsy. We discuss the extent to which response may be specifically attributed to cannabidiol, with consideration and discussion of multiple potential drug-drug interactions. Based on this case, we propose that adjunctive cannabidiol be considered in the treatment of SRSE.

Keywords: Cannabidiol; EEG; Pediatric; Status epilepticus.

Publication types

  • Case Reports