Thalidomide Teratogenic Effects Linked to Degradation of SALL4: After 60 years, researchers have now shed light on the mechanism underlying thalidomide's devastating teratogenic effects

Am J Med Genet A. 2018 Dec;176(12):2538-2539. doi: 10.1002/ajmg.a.61008.
No abstract available

Publication types

  • Letter

MeSH terms

  • Humans
  • Proteolysis / drug effects
  • Teratogenesis / drug effects*
  • Teratogens / pharmacology*
  • Thalidomide / pharmacology*
  • Transcription Factors / genetics
  • Transcription Factors / metabolism*

Substances

  • SALL4 protein, human
  • Teratogens
  • Transcription Factors
  • Thalidomide