Synthesis and antimicrobial activity of some pyrrole derivatives. II: 2-(2'-acylhydrazino)-3-ethoxycarbonyl-5-aryl (or alkyl)- pyrrole derivatives

Farmaco Sci. 1988 Apr;43(4):319-31.

Abstract

A series of 2-(2'-acylhydrazino)-3-ethoxycarbonyl-3-aryl (or alkyl)-pyrrole derivatives was synthesized and submitted to in vitro microbiological screening. Most derivatives showed considerable antibacterial and antifungal activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents / chemical synthesis*
  • Anti-Infective Agents / pharmacology
  • Candida albicans / drug effects
  • Chemical Phenomena
  • Chemistry
  • Hydrazines / chemical synthesis*
  • Hydrazines / pharmacology
  • Magnetic Resonance Spectroscopy
  • Pyrroles / chemical synthesis*
  • Pyrroles / pharmacology
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Hydrazines
  • Pyrroles