Computer-assisted medical image classification for early diagnosis of oral cancer employing deep learning algorithm

J Cancer Res Clin Oncol. 2019 Apr;145(4):829-837. doi: 10.1007/s00432-018-02834-7. Epub 2019 Jan 3.

Abstract

Purpose: Oral cancer is a complex wide spread cancer, which has high severity. Using advanced technology and deep learning algorithm early detection and classification are made possible. Medical imaging technique, computer-aided diagnosis and detection can make potential changes in cancer treatment. In this research work, we have developed a deep learning algorithm for automated, computer-aided oral cancer detecting system by investigating patient hyperspectral images.

Methods: To validate the proposed regression-based partitioned deep learning algorithm, we compare the performance with other techniques by its classification accuracy, specificity, and sensitivity. For the accurate medical image classification objective, we demonstrate a new structure of partitioned deep Convolution Neural Network (CNN) with two partitioned layers for labeling and classify by labeling region of interest in multidimensional hyperspectral image.

Results: The performance of the partitioned deep CNN was verified by classification accuracy. We have obtained classification accuracy of 91.4% with sensitivity 0.94 and a specificity of 0.91 for 100 image data sets training for task classification of cancerous tumor with benign and for task classification of cancerous tumor with normal tissue accuracy of 94.5% for 500 training patterns was obtained.

Conclusions: We compared the obtained results from another traditional medical image classification algorithm. From the obtained result, we identify that the quality of diagnosis is increased by proposed regression-based partitioned CNN learning algorithm for a complex medical image of oral cancer diagnosis.

Keywords: Deep learning algorithm; Hyperspectral image data; Image labeling; Medical image classification; Oral cancer diagnosis.

MeSH terms

  • Algorithms*
  • Deep Learning*
  • Early Detection of Cancer / methods
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Mouth Neoplasms / diagnostic imaging*