Integrating Genomics into Healthcare: A Global Responsibility

Am J Hum Genet. 2019 Jan 3;104(1):13-20. doi: 10.1016/j.ajhg.2018.11.014.


Genomic sequencing is rapidly transitioning into clinical practice, and implementation into healthcare systems has been supported by substantial government investment, totaling over US$4 billion, in at least 14 countries. These national genomic-medicine initiatives are driving transformative change under real-life conditions while simultaneously addressing barriers to implementation and gathering evidence for wider adoption. We review the diversity of approaches and current progress made by national genomic-medicine initiatives in the UK, France, Australia, and US and provide a roadmap for sharing strategies, standards, and data internationally to accelerate implementation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Australia
  • Delivery of Health Care / economics
  • Delivery of Health Care / methods*
  • Delivery of Health Care / organization & administration*
  • Delivery of Health Care / trends
  • Evidence-Based Medicine
  • France
  • Genetics, Medical / economics
  • Genetics, Medical / methods*
  • Genetics, Medical / organization & administration*
  • Genetics, Medical / trends
  • Genomics / economics
  • Genomics / trends*
  • Humans
  • Information Dissemination
  • International Cooperation*
  • Private Sector
  • United Kingdom
  • United States