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. 2018 Dec 4;11:2516865718813122.
doi: 10.1177/2516865718813122. eCollection 2018.

Knowledge, Attitudes, and Practices of Women Toward Prenatal Genetic Testing

Free PMC article

Knowledge, Attitudes, and Practices of Women Toward Prenatal Genetic Testing

Nour Abdo et al. Epigenet Insights. .
Free PMC article


Objectives: We aim to address public knowledge, attitudes, and practices relative to prenatal genetic testing as a starting point for policy development in Jordan.

Study design: We conducted a cross-sectional prenatal genetic testing knowledge, attitudes, and practices survey with 1111 women recruited at obstetrics and gynecology clinics nationwide. Data were analyzed using a variety of descriptive and inferential statistical tests.

Results: The overwhelming majority (>94%) of participants considered prenatal genetic testing, particularly non-invasive prenatal genetic screening, procedures to be good, comfortable, and reasonable, even when the non-diagnostic nature of non-invasive prenatal genetic screening was explained. Likewise, 95% encouraged the implementation of non-invasive prenatal genetic screening within the Jordanian health system, but most preferred it to remain optional. However, women in higher-risk age brackets, in consanguineous marriages, and with less education were significantly less interested in learning about non-invasive prenatal genetic screening. Only 60% of women interviewed were satisfied with the services provided by their obstetric/gynecologist. The more satisfied the women were, the more they are likely to adapt non-invasive prenatal genetic screening.

Conclusions: In sum, although the data support the receptivity of Jordanian women to national implementation of non-invasive prenatal genetic screening, such policies should be accompanied by health education to increase the genetic literacy of the population and to engage high-risk populations. Thus, this offers rare insight into the readiness of 1 particular Arab population to adapt non-invasive prenatal genetic screening technologies.

Keywords: Jordan policy; Prenatal genetic screening; and practices; attitudes; knowledge; non-invasive prenatal genetic screening tests.

Conflict of interest statement

Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.


Figure 1.
Figure 1.
Hierarchy of women’s perception toward GS in general, and the hypothetical act of abortion in case diagnosed a congenital disease (red) or Down syndrome (blue). GS indicates genetic screening. The total numbers are not complete due to missing values.

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