The Pattern of Tpeak-Tend Interval and QTdis, and Pdis in Children with Brucellosis

J Trop Pediatr. 2019 Oct 1;65(5):474-480. doi: 10.1093/tropej/fmy078.

Abstract

Objective: To investigate the effect of inflammation on the conducting system of the heart in patients diagnosed with brucellosis.

Methods: A total of 42 patients diagnosed with brucellosis and 39 age and sex-matched healthy children were enrolled into the study. Pre- and post-treatment electrocardiographic parameters in brucellosis and control group were recorded from an electrocardiogram for each patient.

Results: The results indicated that the parameters including Pmax, Pdis, QTmax, QTdis, QTcdis, Tp-edis interval and Tp-emax/QTmax and Tp-emax/QTcmax ratios, which are known to be key indicators for the prediction of severe atrial or ventricular arrhythmia and sudden cardiac death and also important parameters used as the indicators for the non-invasive evaluation of the transmural heterogeneity were significantly longer in the study group compared with the control group (p < 0.05).

Conclusion: In this study, it was determined that the brucella disease had more cardiac involvement than thought, and this was more in the subclinical form of cardiac involvement.

Keywords: Pdis; Tp-e dis; Tp-e/QT ratio; brucellosis; child; inflammation.

MeSH terms

  • Adolescent
  • Arrhythmias, Cardiac / diagnosis
  • Arrhythmias, Cardiac / etiology*
  • Brucellosis / complications*
  • Brucellosis / physiopathology
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Electrocardiography* / methods
  • Female
  • Heart Murmurs / diagnosis
  • Heart Murmurs / etiology
  • Humans
  • Male