Factor V Leiden

Radiol Technol. 2019 Jan;90(3):259-273.


Factor V Leiden thrombophilia is a genetic mutation that results in hypercoagulation of the blood that presents life-threatening symptoms. This article describes the role of imaging in diagnosis and treatment of cardiovascular complications caused by factor V Leiden and summarizes the etiology, risk factors, symptoms, diagnostic measures, progression, prognosis, and treatment of the mutation.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / diagnostic imaging*
  • Cardiovascular Diseases / genetics*
  • Disease Progression
  • Factor V / genetics*
  • Humans
  • Mutation
  • Prognosis
  • Risk Factors
  • Thrombophilia / genetics*


  • factor V Leiden
  • Factor V

Supplementary concepts

  • Thrombophilia, hereditary