Factors affecting linkage to HIV care and ART initiation following referral for ART by a mobile health clinic in South Africa: evidence from a multimethod study

J Behav Med. 2019 Oct;42(5):883-897. doi: 10.1007/s10865-018-0005-x. Epub 2019 Jan 11.

Abstract

Linkage to care from mobile clinics is often poor and inadequately understood. This multimethod study assessed linkage to care and antiretroviral therapy (ART) uptake following ART-referral by a mobile clinic in Cape Town (2015/2016). Clinic record data (N = 86) indicated that 67% linked to care (i.e., attended a clinic) and 42% initiated ART within 3 months. Linkage to care was positively associated with HIV-status disclosure intentions (aOR: 2.99, 95% CI 1.13-7.91), and treatment readiness (aOR: 2.97, 95% CI 1.05-8.34); and negatively with good health (aOR: 0.35, 95% CI 0.13-0.99), weekly alcohol consumption (aOR: 0.35, 95% CI 0.12-0.98), and internalised stigma (aOR: 0.32, 95% CI 0.11-0.91). Following linkage, perceived stigma negatively affected ART-initiation. In-depth interviews (N = 41) elucidated fears about ART side-effects, HIV-status denial, and food insecurity as barriers to ART initiation; while awareness of positive ART-effects, follow-up telephone counselling, familial responsibilities, and maintaining health to avoid involuntary disclosure were motivating factors. Results indicate that an array of interventions are required to encourage rapid ART-initiation following mobile clinic HIV-testing services.

Keywords: Barriers to ART initiation; Community-based HIV testing services; HIV care continuum; HIV treatment cascade; HIV/AIDS; Linkage to care; Mobile clinic; Qualitative.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Anti-HIV Agents / therapeutic use
  • Drug Utilization / statistics & numerical data*
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / psychology*
  • Health Knowledge, Attitudes, Practice*
  • Health Services Accessibility / statistics & numerical data*
  • Humans
  • Male
  • Mobile Health Units / statistics & numerical data*
  • Motivation
  • Referral and Consultation
  • South Africa
  • Young Adult

Substances

  • Anti-HIV Agents