Malignant extrapleural solitary fibrous tumor arising in the sublingual gland: A case report and review of literature

Oral Oncol. 2019 Mar:90:141-144. doi: 10.1016/j.oraloncology.2018.12.013. Epub 2019 Jan 10.

Abstract

Solitary fibrous tumor is an uncommon neoplasm with unpredictable clinical behavior. Malignant solitary fibrous tumor is a rare morphological variant with more aggressive behavior and higher rates of local recurrences and distant metastasis, exceeding rare in oral cavity; our case occurred in the floor of the mouth in the sublingual gland.

Keywords: ALDH1; Head and neck neoplasm; Malignant extrapleural solitary fibrous tumor; Oral cavity neoplasm; STAT6.

Publication types

  • Case Reports
  • Letter
  • Review

MeSH terms

  • 12E7 Antigen / metabolism
  • Adult
  • Aldehyde Dehydrogenase 1 Family / metabolism
  • Antigens, CD34 / metabolism
  • Female
  • Humans
  • Immunohistochemistry
  • Margins of Excision
  • Proto-Oncogene Proteins c-bcl-2 / metabolism
  • Retinal Dehydrogenase / metabolism
  • Solitary Fibrous Tumors / diagnosis*
  • Solitary Fibrous Tumors / surgery*
  • Sublingual Gland Neoplasms / diagnosis*
  • Sublingual Gland Neoplasms / surgery*
  • Treatment Outcome

Substances

  • 12E7 Antigen
  • Antigens, CD34
  • BCL2 protein, human
  • CD99 protein, human
  • Proto-Oncogene Proteins c-bcl-2
  • Aldehyde Dehydrogenase 1 Family
  • ALDH1A1 protein, human
  • Retinal Dehydrogenase